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Which Analytical Techniques Benefit from 1.5ml Glass High Recovery Vials?

Analytical laboratories rely on a variety of techniques to characterise and quantify chemical compounds. From spectroscopy to chromatography, the choice of sample container can have a significant impact on the accuracy and reproducibility of results. One type of vial that has become increasingly popular in analytical applications is the 1.5ml glass high recovery vial.

 

The importance of sample containment

 

Proper sample containment is essential for reliable analytical measurements. Vial material, dimensions and closure system can all influence factors such as analyte adsorption, solvent evaporation and cross-contamination. Choosing the right vial for a particular application is essential to ensure sample integrity and data accuracy.

 

Analyte adsorption can occur when the sample interacts with the surface of the vial, resulting in loss of the analyte and inaccurate results. Solvent evaporation can change the sample concentration, again leading to measurement errors. Cross contamination can occur when residues from previous samples remain in the vial and interfere with the current analysis. By selecting the appropriate vial, analysts can mitigate these problems and obtain reliable, reproducible data.

 

Advantages of 1.5 mL High Recovery Glass Vials

 

The 1.5 mL High Recovery Glass Vial offers several advantages that make it suitable for a range of analytical techniques:

1. Volume flexibility:

 

The 1.5 mL volume provides ample space for sample preparation and analysis while maintaining a relatively small footprint. This makes the vials ideal for applications where sample availability is limited or where minimising solvent and reagent consumption is important. The 1.5 mL size strikes a balance between providing sufficient volume for the analytical procedure and minimising overall sample and solvent requirements, which can be critical when working with valuable or scarce samples.

2. Inert glass material:

 

Glass is a highly inert material that is compatible with a wide range of solvents and analytes. This helps to minimise the risk of adsorption or leaching, ensuring that the sample composition remains stable throughout the analytical process. Glass is resistant to chemical interactions, making it a reliable choice for holding a wide range of samples without compromising their integrity.

3. High recovery design:

 

The high recovery design of these vials is optimised to minimise the amount of sample left on the vial walls during transfer or extraction. This can be particularly beneficial for trace level analysis or when working with precious or limited samples, helping to ensure that the maximum amount of analyte is available for measurement. The high recovery design reduces sample loss and improves overall analytical sensitivity.

4. Reduced evaporation:

 

The tight-sealing caps and inert glass material of the 1.5 mL vials help prevent solvent evaporation, ensuring that the sample remains at the intended concentration throughout the analysis. Maintaining sample concentration is critical for accurate quantification and the 1.5 mL High Recovery Glass Vials excel at minimising solvent loss, which can be a common problem with smaller volume vials.

5. Improved reproducibility:

 

The consistent dimensions and high quality construction of 1.5 mL High Recovery Glass Vials can contribute to improved method reproducibility by standardising sample handling and injection. The consistent design and reliable performance of these vials help to reduce variability between different samples and across multiple analyses, resulting in more reliable and consistent results.

 

Analytical techniques that benefit from 1.5 mL High Recovery Glass Vials

 

The versatility of 1.5 mL High Recovery Glass Vials makes them suitable for a wide range of analytical techniques, including

1. High performance liquid chromatography (HPLC):

 

The small volume and inert glass material of these vials are well suited to HPLC analysis where sample integrity and accurate quantification are critical. HPLC methods often require small sample volumes and the 1.5 mL vials provide the necessary capacity while maintaining sample purity and minimising potential interactions with the containment material.

2. Gas Chromatography (GC):

 

The 1.5 mL vials can be used for GC applications, particularly when working with volatile or temperature-sensitive analytes that require careful sample handling. The tight-sealing caps and inert glass composition of the 1.5 mL vials help to prevent sample loss or contamination during GC analysis, ensuring reliable results.

3. Mass Spectrometry (MS):

 

The high recovery design and reduced risk of sample loss or contamination make these vials an excellent choice for MS techniques where sample volume and purity are paramount. MS analysis often requires small sample volumes and the 1.5 mL vials can provide the required amount while minimising the risk of analyte adsorption or carry-over between samples.

4. Nuclear magnetic resonance (NMR) spectroscopy:

 

The 1.5 mL glass vials can be used for NMR analysis, providing a compact and inert sample containment solution for structural elucidation and quantification studies. The small volume and consistent dimensions of the 1.5 mL vials are well suited to the specific requirements of NMR analysis, where sample homogeneity and reproducibility are critical to obtaining reliable results.

5. Spectrophotometric analysis:

 

Various spectroscopic techniques such as UV-Vis and fluorescence spectroscopy can benefit from the use of 1.5 mL High Recovery Glass Vials, ensuring accurate and reproducible absorbance or emission measurements. The inert glass material and high recovery design of the 1.5 mL vials help to maintain sample integrity and minimise potential interferences that could affect spectroscopic measurements.

 

By using 1.5 mL High Recovery Glass Vials, analytical laboratories can optimise their workflows, improve data quality and increase the overall efficiency of their analytical processes. The versatility and performance benefits of these vials make them a valuable tool for a wide range of analytical applications.

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